The Structure of 30 nm Chromatin Fiber and Its Regulation 后印本

作者： Liang Dan ¹ Chen Ping ¹ Li Guo-Hong ¹
作者单位：

1. Chinese Acad Sci, Inst Biophys, Natl Lab Biomacromol, Beijing 100101, Peoples R China.
提交时间：2016-05-11 08:40:37

摘要: In eukaryotic cells, genomic DNA is hierarchically packed into chromatin by histones in the nucleus. Despite of over 30 years' study, the fundamental structure of 30 nm chromatin fiber remains controversial. In this review, we focus on recent progress in revealing the structure of 30 nm chromatin fiber, and emphasize on the most recent left-handed double helix structure of 30 nm chromatin fiber. In addition, we discuss the epigenetic regulation of the 30 nm chromatin structure. Finally, we discuss the possible challenge in elucidating the structure of 30 nm chromatin fiber and its regulation.

NUCLEOSOME CORE PARTICLE HISTONE H1 CRYSTAL-STRUCTURE H4-K16 ACETYLATION LINKER HISTONE CRYO-EM ORGANIZATION REVEALS MAINTAIN SUPPORT

分类： 生物学 >> 生物物理学 >> 生物物理、生物化学与分子生物学
引用： ChinaXiv:201605.01319 (或此版本 ChinaXiv:201605.01319V1)
DOI:10.12074/201605.01319V1
CSTR:32003.36.ChinaXiv.201605.01319.V1
科创链TXID： 344a56fb-6a6c-4821-9d13-d084f1271fbc
推荐引用方式： Liang Dan,Chen Ping,Li Guo-Hong.The Structure of 30 nm Chromatin Fiber and Its Regulation.null.[ChinaXiv:201605.01319V1] (点此复制)

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[V1]

2016-05-11 08:40:37

ChinaXiv:201605.01319V1

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