分类： 农、林、牧、渔 >> 农业基础学科 提交时间： 2025-02-21 合作期刊: 《干旱区科学》
摘要： The Tarim River Basin (TRB) is a vast area with plenty of light and heat and is an important base for grain and cotton production in Northwest China. In the context of climate change, however, the increased frequency of extreme weather and climate events is having numerous negative impacts on the region's agricultural production. To better understand how unfavorable climatic conditions affect crop production, we explored the relationship of extreme weather and climate events with crop yields and phenology. In this research, ten indicators of extreme weather and climate events (consecutive dry days (CDD), min Tmax (TXn), max Tmin (TNx), tropical nights (TR), warm days (Tx90p), warm nights (Tn90p), summer days (SU), frost days (FD), very wet days (R95p), and windy days (WD)) were selected to analyze the impact of spatial and temporal variations on the yields of major crops (wheat, maize, and cotton) in the TRB from 1990 to 2020. The three key findings of this research were as follows: extreme temperatures in southwestern TRB showed an increasing trend, with higher extreme temperatures at night, while the occurrence of extreme weather and climate events in northeastern TRB was relatively low. The number of FD was on the rise, while WD also increased in recent years. Crop yields were higher in the northeast compared with the southwest, and wheat, maize, and cotton yields generally showed an increasing trend despite an earlier decline. The correlation of extreme weather and climate events on crop yields can be categorized as extreme nighttime temperature indices (TNx, Tn90p, TR, and FD), extreme daytime temperature indices (TXn, Tx90p, and SU), extreme precipitation indices (CDD and R95p), and extreme wind (WD). By using Random Forest (RF) approach to determine the effects of different extreme weather and climate events on the yields of different crops, we found that the importance of extreme precipitation indices (CDD and R95p) to crop yield decreased significantly over time. As well, we found that the importance of the extreme nighttime temperature (TR and TNx) for the yields of the three crops increased during 2005–2020 compared with 1990–2005. The impact of extreme temperature events on wheat, maize, and cotton yields in the TRB is becoming increasingly significant, and this finding can inform policy decisions and agronomic innovations to better cope with current and future climate warming.
分类： 生物学 >> 生物物理学 >> 生物物理、生物化学与分子生物学 提交时间： 2016-05-18
Wu, Yanwei
Wu, Yanwei
Cheng, Shiya
Zou, Wei
Wang, Xiaochen
Zhao, Hongyu
Zhang, Hong
Yoshina, Sawako
Mitani, Shohei
Yoshina, Sawako
Mitani, Shohei
摘要： Autophagosome formation is promoted by the PI3 kinase complex and negatively regulated by myotubularin phosphatases, indicating that regulation of local phosphatidylinositol 3-phosphate (PtdIns3P) levels is important for this early phase of autophagy. Here, we show that the Caenorhabditis elegans myotubularin phosphatase MTM-3 catalyzes PtdIns3P turnover late in autophagy. MTM-3 acts downstream of the ATG-2/EPG-6 complex and upstream of EPG-5 to promote autophagosome maturation into autolysosomes. MTM-3 is recruited to autophagosomes by PtdIns3P, and loss of MTM-3 causes increased autophagic association of ATG-18 in a PtdIns3P-dependent manner. Our data reveal critical roles of PtdIns3P turnover in autophagosome maturation and/or autolysosome formation.
分类： 生物学 >> 生物物理学 >> 细胞生物学 提交时间： 2016-05-12
Zhang, Hong
Guo, Bin
Lin, Long
Lu, Qun
Wu, Fan
Chang, Jessica T.
Hansen, Malene
Kumsta, Caroline
Lapierre, Louis R.
Jia, Kailiang
Kovacs, Attila L.
Legouis, Renaud
Melendez, Alicia
Melendez, Alicia
O'Rourke, Eyleen J.
Sato, Ken
Sato, Miyuki
Wang, Xiaochen
摘要： The cellular recycling process of autophagy has been extensively characterized with standard assays in yeast and mammalian cell lines. In multicellular organisms, numerous external and internal factors differentially affect autophagy activity in specific cell types throughout the stages of organismal ontogeny, adding complexity to the analysis of autophagy in these metazoans. Here we summarize currently available assays for monitoring the autophagic process in the nematode C. elegans. A combination of measuring levels of the lipidated Atg8 ortholog LGG-1, degradation of well-characterized autophagic substrates such as germline P granule components and the SQSTM1/p62 ortholog SQST-1, expression of autophagic genes and electron microscopy analysis of autophagic structures are presently the most informative, yet steady-state, approaches available to assess autophagy levels in C. elegans. We also review how altered autophagy activity affects a variety of biological processes in C. elegans such as L1 survival under starvation conditions, dauer formation, aging, and cell death, as well as neuronal cell specification. Taken together, C. elegans is emerging as a powerful model organism to monitor autophagy while evaluating important physiological roles for autophagy in key developmental events as well as during adulthood.
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